ALSP Publications

Inhibitors of Cathespin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor Protein Biological Chemistry, (2008) 283:7745-7753 by Hook, V. Y. H. and G. Hook et al.

Cysteine Protease Inhibitors Effectively Reduce In Vivo Levels of brain β-amyloid Related to Alzheimer’s Disease Biological Chemistry, (2007) 388:247-252 by Hook, V. et al.

Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate β-secretase of Alzheimer’s disease Biological Chemistry, (2005) 386: 931-940 by Hook, V. et al.

Cysteine Proteases Are the Major β-Secretase in the Regulated Secretory Pathway That Provides Most of the β-Amyloid in Alzheimer’s Disease: Role of BACE 1 in the Constitutive Secretory Pathway Journal of Neuroscience Research, (2003) 74: 393-405 by Hook, V. Y. H. and T. D. Reisine

β-Amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for β-secretase activity in chromaffin vesicles Journal of Neurochemistry, (2002) 82: 237-256 by Hook, V. et al.